The 007 star trades his signature suit for a flowing blond wig, dress, pearls and sensible heels in the somber clip which highlights inequalities faced by women around the world.
The video — narrated by actress Judi Dench, recreating her role as spymaster M — notes Bond's "fondness for women" but asks if the suited spy has "ever considered what it might like to be one."
A silent Bond reappears on camera and strikes a seemingly confident pose in drag. As M rattles off statistics on sexual violence, education and pay inequality, Craig pulls off the wig and earrings.
He exits the screen when asked "So, are we equals?"