[UPDATE Mar. 19 at 6:04 a.m.] Anchorage police have reopened the Seward Highway as of 2:52 a.m. Wednesday.

[STORY Mar. 18 at 7:31 p.m.] Anchorage police say one person died in a car-semi truck collision that has closed the Seward Highway near Potter Marsh Tuesday night.

Police at the scene say the car was headed south with a female driver, who was pronounced dead after colliding with a double-trailer fuel semi truck headed north. Neither vehicle was carrying passengers, and the semi wasn't carrying chemicals or toxins.

Initial reports of the crash, which APD spokesperson Jennifer Castro says came in at at about 7:15 p.m., described the small car as unrecognizable after the collision. One person in the car was reportedly unconscious, while the semi’s driver was conscious and breathing.

A Channel 2 crew saw the semi in the ditch on the west side of the highway facing north, between it and nearby Alaska Railroad tracks, with at least four Anchorage Fire Department units at the scene.

One man at the scene wearing a sling was being questioned by police, while several firefighters and medics were tending to another person.

Police say the highway is still closed near the Potter Marsh boardwalk as of 11 p.m. Tuesday, and will remain so APD's investigative unit has finished examining the crash site. Officers advise drivers to turn around and find alternate routes.

In a statement shortly before 9 p.m. Tuesday, Castro says a detour onto the Old Seward Highway, Rabbit Creek Road and Potter Marsh Road will allow people to pass the crash site on the east side of the marsh.

"APD will be notifying next-of-kin before the identity of the deceased is released," Castro wrote. "The APD Traffic Investigation Unit is on-scene investigating the crash as well as the Department of Transportation."

Channel 2's Caslon Hatch contributed information to this story.